|1.1||Classification of enzymes – six major classes of enzymes with one example each.||2||2|
|1.2||Elementary study of the factors affecting velocity of enzyme catalyzed reactions- effect of substrate concentration.||1||2|
|1.3||Elementary study of the factors affecting velocity of enzyme catalyzed reactions- effect of enzyme concentration.||1||2|
|1.4||Elementary study of the factors affecting velocity of enzyme catalyzed reactions- effect of temperature.||1||2|
|1.5||Elementary study of the factors affecting velocity of enzyme catalyzed reactions- effect of pH.||1||2|
|1.6||Michaelis-Menten equation. Km and its significance.||1||2|
|1.7||The Lineweaver-Burk plot.||2||2|
|1.8||Cofactors and coenzymes||2||3|
|1.9||Group specificity of enzyme with example.||1||4|
|1.10||Optical specificity of enzyme with example.||1||4|
|1.11||Geometrical specificity of enzyme with example.||1||4|
|1.12||Cofactor specificity of enzyme with example.||1||4|
|2.1||Glycolysis (with structure).||3||5|
|2.2||Fates of pyruvate – lactic acid fermentation.||1||5|
|2.3||Fates of pyruvate – alcohol fermentation.||1||5|
|2.4||Pyruvate dehydrogenase reaction.||1||5|
|2.5||Citric acid cycle (with structure).||3||5|
|2.6||Substrate level phosphorylation.||1||5|
|2.7||Electron transport chain.||2||5|
|2.9||Glycogen metabolism – glycogenesis.||1||5|
|3.1||Decarboxylation of aminoacids.||2||6|
|3.2||Deamination of aminoacids.||1||6|
|3.3||Transamination of aminoacids.||2||6|
|3.5||Glucogenic amino acids with examples.||2||8|
|3.6||Ketogenic amino acids with examples.||2||8|
|4.1||Fatty acid biosynthesis (with structure).||3||9|
|4.2||Oxidation of fatty acids – Fatty acid activation.||1||10|
|4.3||Oxidation of fatty acids – Carnitine shuttle.||1||10|
|4.4||β-Oxidation of fatty acids (with structure) – explain using palmitic acid and ATP yield.||2||10|
|4.6||Cholesterol biosynthesis (without structure).||2||12|
Text Books for Reference
A Text Book of Biochemistry by E.S. West, W.R. Todd, H.S. Mason and J.T. van Bruggen, Oxford and IBH Publishing Co., New Delhi, 1974.
Harper’s Biochemistry by Robert K. Murray , Daryl K. Granner, Peter A. Mayes and Victor W. Rodwell, Publisher: Appleton & Lange; 25th Revised edition (1 July 1999), ISBN-10: 0838536840, ISBN-13: 978-0838536841.
Biochemistry Seventh Edition by Jeremy M. Berg, John L. Tymoczko and Lubert Stryer, 74 Publisher: W. H. Freeman; Seventh Edition edition (December 24, 2010).
Text Books for Enrichment
Biochemistry by Donald Voet, Judith G. Voet, Publisher: John Wiley & Sons (2011), Fourth Edition, ISBN-10: 0071737073, ISBN-13: 978-0071737074.
Fundamentals of Biochemistry by J. L. Jain, Sunjay Jain, Nithin Jain (2008), Publishers: S. Chand & Co Ltd ISBN: 81-219-2453-7.
Lehninger, Principles of Biochemistry by Nelson, D. L., Lehninger, A. L., & Cox, M. M.(2008), 5thEdition, ISBN: 978-0-230-22699-9, Publisher: W. H. Freeman and Company, New York, p: 677-878.