SYLLABUS

Module

Course Description Hrs CO.No.
1.0 NUTRITIONAL BIOCHEMISTRY 12  
1.1 Concepts of nutrition, Nutritional requirements. 1 1
1.2 Principle foods – cereals, pulses, vegetables, fruits. 1 1
1.3 Principle foods – nuts, milk, egg, meat, fish. 1 1
1.4 Calorific value of foods. 1 1
1.5 Respiratory quotient, Basal metabolic rate. 1 1
1.6 Biological value of proteins, essential and nonessential amino acids. 1 1
1.7 Biological value of essential and non-essential fatty acids 1 1
1.8 Sources, nutritional importance and deficiency disorders of vitamin A, D, E and K. 1 2
1.9 Sources, nutritional importance and deficiency disorders of vitamin C, B1, B2, and pyridoxine. 1 2
1.10 Sources, nutritional importance and deficiency disorders of vitamin B12, nicotinic acid and folicacid. 1 2
1.11 Biological and nutritional importance of macro minerals -calcium, magnesium, sodium and potassium and their deficiency disorders. 1 2
1.12 Biological and nutritional importance of micro minerals -iron, copper and selenium and their deficiency disorders. 1 2
2.0 BLOOD 10  
2.1 Constituents of Blood. 1 3
2.2 Types of blood cells. 1 3
2.3 Components of plasma. 1 4
2.4 Types of plasma proteins and functions. 1 4
2.5 Mechanism of blood clotting – Extrinsic pathway. 1 5
2.6 Mechanism of blood clotting – Intrinsic pathway. 1 5
2.7 Anticoagulants. 1 5
2.8 Fibrinolysis. 1 5
2.9 Structure of hemoglobin. 1 6
2.10 Types of hemoglobin, sickle cell anemia. 1 7
3.0 CLINICAL BIOCHEMISTRY 18  
3.1 Basic concepts of clinical biochemistry. 1 8
3.2 Definition and scope of clinical biochemistry in diagnosis. 1 8
3.3 Sample collection and preservation of blood 1 8
3.4 Sample collection and preservation of plasma and serum. 1 8
3.5 Sample collection and preservation of urine. 1 8
3.6 Chemical analysis of blood. 1 8
3.7 Chemical analysis of urine. 1 8
3.8 Chemical analysis of CSF. 1 8
3.9 Liver function tests – Total protein, albumin, globulin, albumin -globulin ratio. 1 8
3.10 Liver function tests – Total bilirubin and conjugated bilirubin 1 8
3.11 Liver function tests – AST, ALT. 1 8
3.12 Liver function tests – ALP, GTT. 1 8
3.13 Thyroid function tests – T3 and T4. 1 8
3.14 Thyroid function tests – TSH. 1 8
3.15 Renal function tests – Urea. 1 8
3.16 Renal function tests –Creatinine. 1 8
3.17 Renal function tests – Urea clearance test. 1 8
3.18 Renal function tests – Creatinine clearance test. 1 8
4.0 BIOCHEMICAL BASIS OF METABOLIC DISORDERS 14  
4.1 Biochemical basis of Lactose intolerance. 1 9
4.2 Biochemical basis of Diabetes mellitus. 4 9
4.3 Biochemical basis of hypoglycaemia. 1 9
4.4 Biochemical basis of galactosemia 1 9
4.5 Biochemical basis of hyperlipidemia. 2 9
4.6 Biochemical basis of atherosclerosis. 1 9
4.7 Biochemical basis of ketosis. 2 9
4.8 Biochemical basis of obesity. 2 9

Text Books for Reference

 Lehninger Principles of Biochemistry by Nelson, D. L., Lehninger, A. L., & Cox, M. M. (2008) 5thEdition, ISBN: 978-0-230-22699-9, Publisher: W. H. Freeman and, Company, New York p:43-64.

 Clinical Biochemistry: Metabolic And Clinical Aspects by William J. Marshall, Stephan K. Bangert, Elizabeth S.M. Ed. S.M (ed) Marshall (2008) Publisher: Elsevier Science Health Science Div ISBN: 0443101868 ISBN-13: 9780443101861, 978-0443101861

 Biochemistry by John K. Joseph (2006) Publisher: Campus Books International ISBN: 8180301109 ISBN -13: 9788180301100, 978-8180301100.

 Basic Medical Biochemistry: A Clinical Approach by Dawn B PH.D. Marks, Allam D. Marks colleen M. Smith (1996) Publisher; Lippincott Williams & Wilkins; illustrated edition ISBN -10: 068305595X ISBN-13: 978-0683055955

 Notes on Clinical Biochemistry by John K. Candlish (1992) publisher: World Scientific Publishing Company ISBN: 9810210663 ISBN-13: 9789810210663, 978-9810210663

Text Books for Enrichment

 A Text Book of Biochemistry by E.S. West, W.R. Todd, H.S. Mason and J.T. van Bruggen, Oxford and IBH Publishing Co., New Delhi, 1974

 Biochemistry (2004) by Donald Voet, Judith G. Voet Publisher: John Wiley & Sons Inc ISBN: 047119350X ISBN-13: 9780471193500, 978-0471193500

 Principles Of Biochemistry (1995) by Geoffrey L Zubay, William W Parson, Dennis Evance Publisher: Mcgraw-hill Book Company Koga ISBN:0697142752 ISBN-13: 9780697142757, 978-0697142757

 Principles Of Biochemistry, 4/e (2006) by Robert Horton H , Laurence A Moran, GrayScrimgeourK Publisher: Pearsarson ISBN: 0131977369, ISBN-13:9780131977365, 978-0131977365

 Biochemistry 6th Edition (2007) by Jeremy M.berg John L.TymoczkoLUbertStryer Publisher: B.I. Publications Pvt. Ltd ISBN:071676766X ISBN13: 9780716767664, 978- 716767664

 Biochemistry (2008) by Rastogi Publisher: McgrawHill ISBN:0070527954 ISBN13: 978 0070527959, 978-0070527959