Syllabus

Module Course Description Hrs CO.No.
1.0 CARBOHYDRATES 10      
1.1 Isomerism of carbohydrates – D and L forms of glyceraldehyde. 1 1
1.2 Isomerism of carbohydrates – epimers, anomers. 1 1
1.3 Isomerism of carbohydrates – mutarotation and its explanation by ring structures. 1 1
1.4 Linear and cyclic structures of glucose, galactose, mannose and fructose. 1 1
1.5 Haworth perspective formula of disaccharides – maltose, sucrose, lactose. 1 1
1.6 Structure and important properties of Homo polysaccharides – Starch, Glycogen. 1 1
1.7 Structure and important properties of Homo  polysaccharides –Cellulose and Chitin 1 1
1.8 Structure and important properties of Hetero polysaccharides –Hyaluronic acid. 1 1
1.9 Structure and important properties of Hetero polysaccharides – Heparin. 1 1
1.10 Reducing action of sugars. 1 2
2.0 LIPIDS 6  
2.1 Basic ideas about classification and physiological functions of lipids. 1 3
2.2 Classification of Fatty acids. 1 3
2.3 Structure of stearic acid, oleic acid, linoleic acid and triacyglycerol 1 4
2.4 Structure of phosphatidic acid, lecithin, cephalin and phosphatidyl serine 1 4
2.5 Functions of Sphingolipids. Chemical structure and functions of cholesterol and ergosterol. 1 4
     2.6 Definition of saponification number, acid number and iodine number of fats.    1       5
3.0 AMINOACIDS AND PROTEIN 10  
3.1 Name (with one letter and three letter code) and structures of the 20 standard aminoacids occurring in proteins. 3 6
3.2 Representation of amino acid in the zwitter ionic form 1 6
3.3 Classification and function of Proteins. 1 7
3.4 Elementary study of primary structure of proteins. 1 8
3.5 Elementary study of secondary structure of proteins. 1 8
3.6 Elementary study of tertiary and quaternary structure of proteins. 1 8
3.7 Specialised proteins – structure and functions of collagen 1 8
3.8 Denaturation of proteins. 1 9
4.0 NUCLEIC ACIDS 10  
4.1 Chemical nature of nucleic acids – Structure of purines. 1 10
4.2 Chemical nature of nucleic acids – Structure of pyrimidines. 1 10
4.3 Chemical nature of nucleic acids – Structure of deoxyribose, ribose, nucleosides, nucleotides. 1 10
4.4 Chemical nature of nucleic acids – Formation of phosphodiester linkage 1 10
4.5 Watson -Crick model of DNA, Chargaff rule 1 10
4.6 Different forms of DNA – A, B and Z DNA. 1 10
4.7 Structure and function of mRNA and rRNA. 1 10
4.8 Structure and function of tRNA. 1 11
4.9 Denaturation of nucleic acids – hyperchromic effect. 1 12
4.10 Denaturation of nucleic acids – Tm values and their significance. 1 12

Text Books for Reference

 A Text Book of Biochemistry by E.S. West, W.R. Todd, H.S. Mason and J.T. van Bruggen, Oxford and IBH Publishing Co., New Delhi, 1974.

 Biochemistry by Donald Voet, Judith G. Voet Publisher: John Wiley &Sons Inc(2004) ISBN: 047119350X ISBN-13: 9780471193500, 978-0471193500.

 Principles Of Biochemistry by Geoffrey L Zubay, William W Parson, Dennis E Vance Publisher: Mcgraw-hill Book Company – Koga(1995) ISBN:0697142752 ISBN-13: 9780697142757, 978-0697142757.

 Principles Of Biochemistry, 4/e by Robert Horton H , Laurence A Moran, Gray Scrimgeour K Publisher: Pearsarson(2006) ISBN: 0131977369, ISBN13:978013197736 5, 978-0131977365.

 

Text Books for Enrichment

 Biochemistry (6thEdition) by Jeremy M. Berg, John L. Tymoczko Lubert Stryer Publisher:B.I publications Pvt.Ltd (2007) ISBN:071676766X ISBN13: 978071676 7664,978716767664.

 Fundamentals of Biochemistry by J. L. Jain, Sunjay Jain and Nitin Jain, (2008) Publishers: S. Chand &Co Ltd ISBN: 81-219-2453-7 p:73.

 Lehninger Principles of Biochemistry by Nelson, D. L., Lehninger, A. L., & Cox, M. M. (2008) 5thEdition, ISBN: 978-0-230-22699-9, Publisher: W. H. Freeman and, Company, New York p: 239-255.